Everything You Need to Know About Salmon DNA
Everything You Need to Know About Salmon DNA with PLENHYAGE XL & Medium
Treatments | Written by Radiance | 20 May 2025
Looking for a way to restore your skin’s natural vitality without going under the knife? Polynucleotide-based treatments like PLENHYAGE XL and Medium by BioFormula offer a gentle yet effective approach to skin regeneration. Whether you’re addressing under-eye circles, loss of elasticity, or dull, tired skin, this next-generation injectable might be the solution you’ve been waiting for.
Photo by Ameela Skin.
What Are Polynucleotides?
Polynucleotides are naturally occurring DNA fragments, originally derived from salmon DNA, known for their powerful regenerative properties. When injected into the skin, they activate fibroblasts—the cells that produce collagen and elastin—promoting tissue repair and deep hydration.
Meet PLENHYAGE: XL and Medium
PLENHYAGE Medium is ideal for delicate areas like the under-eyes, early signs of ageing, or sensitive skin. PLENHYAGE XL is designed for more intensive repair, ideal for mature skin, deep wrinkles, or areas such as the hands, neck, or body.
- Stimulates collagen and elastin production
- Reduces inflammation and oxidative stress
- Improves hydration and skin density
- Supports tissue healing and reduces pigmentation
- Safe for use in sensitive areas and all skin types
Benefits Backed by Science
- Up to 115% improvement in skin hydration
- Over 50% increase in skin thickness
- Visible improvement in fine lines, tone, and texture
- Effective for acne scars, pigmentation, and under-eye hollows
Combine for Enhanced Results
PLENHYAGE treatments can be used alone or alongside other procedures to enhance results and accelerate healing:
- Microneedling: Creates channels for deeper penetration, boosting the regenerative effect of polynucleotides.
- Fat Dissolving Injections: Improve skin quality in treated areas by tightening and repairing loose skin post-fat reduction.
- RF Microneedling: Combines radiofrequency with controlled skin injury to stimulate deep collagen remodeling and tighten lax skin.
Result from Combine Treatments: Polynuclotides, Fat Dissolving and RF Microneedling.
What to Expect During Treatment
- You should book a consultation to assess your skin goals and determine the right PLENHYAGE formulation.
- After, your skin is cleansed, and the product is gently injected using a micro-needle or cannula.
- If combined with microneedling or RF, the product is infused during or after the treatment.
- Mild redness or swelling may occur but usually subsides within 1–3 days.
Who Is It For?
PLENHYAGE is suitable for a wide range of concerns:
- Fine lines and early wrinkles
- Dehydrated or dull skin
- Sun-damage and pigmentation
- Scarring and post-acne marks
- Under-eye circles and thinning skin
- Loose or crepey skin on the face, neck, or body
Why We Use PLENHYAGE at Radiance
We only use clinically-backed products like PLENHYAGE that offer visible, restorative effects without aggressive intervention. Each session is tailored to your skin’s unique needs and performed by a qualified aesthetic practitioner in a safe, professional environment.
Is It Safe?
Yes. Polynucleotide treatments are biocompatible, sterile, and FDA-approved. PLENHYAGE is well-tolerated, even in sensitive areas, with minimal risk of side effects.
Now that you know everything About Salmon DNA. Book a Consultation
If you’re looking for a gentle, regenerative way to rejuvenate your skin, get in touch to find out how PLENHYAGE and polynucleotides can help you look refreshed, naturally.
Support your skin’s biology. Rebuild from within. Reveal healthier skin—with polynucleotide therapy at Radiance.